http://hardtlab.com/ 2026-05-01T03:58:24+00:00 http://hardtlab.com/ http://hardtlab.com/lib/tpl/dokuwiki/images/favicon.ico text/html 2023-07-15T15:19:59+00:00 Anonymous (anonymous@undisclosed.example.com) http://hardtlab.com/doku.php?id=projects:decay&rev=1689448799&do=diff Active Decay of Long-Term Memory Our group discovered that the natural loss of long-term memory over time involves the activity-dependent removal of GluA2/AMPARs from post-synaptic sites. Currently, we are studying cellular signalling pathways involved in this active decay process, focussing on known proteins interacting with GluA2/AMPARs at post-synaptic compartments, and the relevant signalling events. text/html 2023-07-15T15:19:59+00:00 Anonymous (anonymous@undisclosed.example.com) http://hardtlab.com/doku.php?id=projects:habitat&rev=1689448799&do=diff The Habitat Based on the view that without forgetting normal brain function would not be possible, the need arose to study the behaviour of rodents within ethologically valid settings. Standard laboratory housing deprives rats of opportunities to express the full range of their natural behaviours, and their physiology reflects this. Thus, experiments with rats living in standard housing, with little change to daily routines, may limit the epistemological and translational value of studies on th… text/html 2023-07-15T15:19:59+00:00 Anonymous (anonymous@undisclosed.example.com) http://hardtlab.com/doku.php?id=projects:interference&rev=1689448799&do=diff Memory Interference Our findings and theoretical predictions suggest that the forgetting mechanisms targeting recent memories or reactivated long-term memories are different from those targeting “dormant” long-term memories. In our current studies on the forgetting of recent (or “active”) memories, we explore the role of memory interference.